diclofenac and (3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid

diclofenac has been researched along with (3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's2 (40.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dayer, P; Leemann, T; Transon, C; Vogt, N1
Appel, S; Hitzenberger, G; Kalafsky, G; Kallay, Z; Kutz, K; Rüfenacht, T; Tetzloff, W1
Andersson, TB; Bredberg, E; Ericsson, H; Sjöberg, H1
Dansette, PM; Jaouen, M; Johnson, EF; Macherey, AC; Mansuy, D; Marques-Soares, C; Melet, A; Sari, MA; Schoch, GA1
Abe, O; Kimura, J; Misaka, S; Ono, T; Onoue, S; Sato, H; Shikama, Y; Yabe, H1

Trials

3 trial(s) available for diclofenac and (3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid

ArticleYear
Lack of interaction between fluvastatin and oral hypoglycemic agents in healthy subjects and in patients with non-insulin-dependent diabetes mellitus.
    The American journal of cardiology, 1995, Jul-13, Volume: 76, Issue:2

    Topics: Administration, Oral; Anticholesteremic Agents; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Diclofenac; Drug Interactions; Fatty Acids, Monounsaturated; Fluvastatin; Glyburide; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Insulin; Lovastatin; Placebos; Simvastatin; Tolbutamide

1995
An evaluation of the in vitro metabolism data for predicting the clearance and drug-drug interaction potential of CYP2C9 substrates.
    Drug metabolism and disposition: the biological fate of chemicals, 2004, Volume: 32, Issue:7

    Topics: Adult; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Chromatography, Liquid; Cross-Over Studies; Cytochrome P-450 CYP2C9; Diclofenac; Drug Interactions; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Ibuprofen; In Vitro Techniques; Indoles; Male; Mass Spectrometry; Microsomes, Liver; Middle Aged; Tolbutamide

2004
Lack of pharmacokinetic interaction between fluvastatin and green tea in healthy volunteers.
    European journal of clinical pharmacology, 2018, Volume: 74, Issue:5

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Catechin; Cross-Over Studies; Cytochrome P-450 CYP2C9; Diclofenac; Fatty Acids, Monounsaturated; Female; Fluvastatin; Food-Drug Interactions; Healthy Volunteers; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Male; Tea; Young Adult

2018

Other Studies

2 other study(ies) available for diclofenac and (3S,5S,6E)-7-[3-(4-fluorophenyl)-1-(propan-2-yl)-1H-indol-2-yl]-3,5-dihydroxyhept-6-enoic acid

ArticleYear
In vivo inhibition profile of cytochrome P450TB (CYP2C9) by (+/-)-fluvastatin.
    Clinical pharmacology and therapeutics, 1995, Volume: 58, Issue:4

    Topics: Adult; Anticholesteremic Agents; Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diclofenac; Drug Interactions; Enzyme Inhibitors; Fatty Acids, Monounsaturated; Female; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Male; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases

1995
Analysis of human cytochrome P450 2C8 substrate specificity using a substrate pharmacophore and site-directed mutants.
    Biochemistry, 2004, Dec-14, Volume: 43, Issue:49

    Topics: Amiodarone; Animals; Arginine; Aryl Hydrocarbon Hydroxylases; Asparagine; Catalysis; Chromans; Computer Simulation; Cytochrome P-450 CYP2C8; Diclofenac; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Indoles; Isoleucine; Models, Molecular; Mutagenesis, Site-Directed; Paclitaxel; Phenylalanine; Rabbits; Serine; Substrate Specificity; Sulfonamides; Thiazolidinediones; Tretinoin; Troglitazone

2004